Generic medicines & the indicate Ingredients - GenMed Shoppes
Generic medicines and the ingredients used in them
We get to hear the term Generic medicines quite often. These medicines are also over-the-counter medicines. However, it is always preferable that medication is taken as per the doctor’s advice. Generic medications contain the same active pharmaceutical ingredients that are used in specific ingredients. They have the same effect on the body as brand-name medicines.
However, generic medicines can be solved under a different name as they contain different inactive ingredients. These inactive ingredients are the ones that give the medicine its tastes, shape, texture, smell, etc. that do not have a direct connection with the treatment and do not affect the medicinal impact.
Although specific drugs might be associated with a particular brand or company that manufactures these medicines, generic drugs are subject to the government regulatory norms associated with the country they are sold in. They are labeled with the name of the manufacturer or a generic non-proprietary name like the International Non-Proprietary Name (INN).
The Food and Drug Associations (FDA) generally insist that the generic medications should be bio-equivalent to their branded counterparts concerning pharmaceutical and pharmacodynamic properties.
Essentially, bio-equivalence may not mean that they should be the exact copy of the branded medicines. However, the therapeutic effect must be the same. Two medicines are considered bio-equivalent when the values obtained from bio-equivalence testing are in the accuracy range between 80-125%. This means the average peak plasma concentration and the time to reach the average peak plasma concentration should not be more than 20% average value.
Generic medicine must undergo rigorous tests and needs formal approval before manufacturing and marketing.